Re-Orienting Planning Practice

Re-orienting the immune system

The blockade of immune regulatory checkpoints is emerging as a powerful anticancer strategy. We recently reported long-term results from the first-in-human clinical trial of anti-PD1 antibody-based immunotherapy, demonstrating durable tumor control off-therapy in subjects affected by colorectal and kidney cancer, as well as successful re-induction therapy in a melanoma patient.

Re-planning with Minimal Perturbation

Mixed Integer Programming (MIP) models are known to be sensitive to slight changes. In this study, we measure the perturbation to a production plan that occurs when re-planning is carried-on due to new orders arrival. Perturbation level is measured using well known metrics: (1) the Hamming distance, (2) the edit distance, and (3) the Damerau-Levenshtein distance. We propose three alternative fo...

Orienting family medicine residents and medical students to office practice.

(Fam Med 2005;37(7):461-3.) Editor’s Note: In this month’s column, Sweety Jain, MD, of the Sacred Heart Hospital Family Practice Residency in Allentown, Pa, discusses important items that should be discussed with residents and students when orienting them to office practice. I welcome your comments about this feature, which is also published on the STFM Web site at www.stfm.org. I also encourag...

Orienting the physical therapist to public health practice.

Acquaintance model in re-planning and re-configuration

The problems of re-configuration and re-planing in multi-agent systems exploring acquaintance models of their behavior are discussed throughout this paper. Both the autonomous and supervised methods of replaning are distinguished. The advantages of the tri-base acquaintance models used in the ProPlanT production planning system for solving the reconfiguration and re-planing tasks are sketched.